The missing links in obesity: Glycemic Index and Insulin

Obesity is among the most important medical problems in the United States today. Currently, 1 in 4 children and 1 in 2 adults are overweight, and prevalence rates that have increased by 50% since the 1960s. The Federal government and various official medical agencies, at the behest of grain producers, have advocated decreasing intake of total fat, while increasing consumption of “complex carbohydrate.” Consumption of carbohydrates has increased over the years, and the nation’s levels of obesity, Type 2 diabetes and heart disease have dramatically risen.  Americans, on average, eat 250 to 300 grams of carbs a day, accounting for about 55% of their caloric intake.

All carbohydrates (a category including sugars) convert to sugar in the blood, and the more refined the carbs are, the quicker the conversion. When you eat a glazed doughnut or a serving of mashed potatoes, it turns into blood sugar very quickly. To manage the blood sugar, the pancreas produces insulin, which pushes glucose from the blood stream into cell to be used for energy conversion or storage.

When cells become more resistant to those insulin instructions, the pancreas needs to make more insulin to push the same amount of glucose into cells. As people become insulin resistant, carbs become a bigger challenge for the body. When the pancreas gets exhausted and can’t produce enough insulin to keep up with the glucose in the blood, diabetes develops

The first sign of insulin resistance is a condition called metabolic syndrome — a red flag for impending diabetes and  heart disease. Metabolic syndrome (found in nearly 1/4 of adults) is diagnosed when people have three or more of the following:

  • high blood triglycerides (more than 150 mg)
  • high blood pressure (over 135/85)
  • central obesity (a waist circumference in men of more than 40 inches and in women, more than 35 inches)
  • low HDL cholesterol (under 40 in men, under 50 in women)
  • elevated fasting glucose.

Glycemic Index measures the “effect of food on blood glucose levels.” It is a ranking of foods based on the how quickly the blood sugar levels will increase after ingestion. A low glycemic food gives a slow increase in blood sugar levels. A high glycemic index food gives a more rapid rise in blood sugar levels.

GI is specifically defined as the measurable glucose response curve after consumption of 50 g carbohydrate from a test food, divided by the response after consumption of 50 g glucose.

 

The GI for glucose would be defined as 100.

  • High GIs are above 50
  • Intermediate GIs range between 35 and 50
  • Low GIs are below or equal to 35

[learn_more caption=”High Glycemic Index Foods (GI>50)”]

Corn syrup 115
Beer 110
Glucose (dextrose) 100
Modified starch 100
Glucose syrup 100
Wheat syrup, rice syrup 100
Fried potatoes, scalloped potatoes 95
Potato flour (starch) 95
Rice flour 95
Maltodextrin 95
Potatoes, oven cooked 95
Potato flour 90
Gluten-free white bread 90
Sticky rice 90
Arrow-root 85
Celeriac, knob celery, turnip rooted celery (cooked) 85
Hamburger buns 85
Maizena (corn starch) 85
Pop corn (without sugar) 85
Rice cake/pudding 85
Tapioca 85
White sandwich bread 85
Carrots (cooked) 85
Corn flakes 85
Instant/parboiled rice 85
Parsnip 85
Puffed rice 85
Rice milk 85
Turnip (cooked) 85
White wheat flour 85
Mashed potatoes 80
Lasagna (soft wheat) 75
Rice milk (with sugar) 75
Waffle (with sugar) 75
Doughnuts 75
Pumpkin, gourd 75
Squash/marrow (various) 75
Watermelon 75
Bagels 70
Biscuit 70
Cabbage turnip, rutabaga, Swede turnip 70
Cola drinks, soft drinks, sodas 70
Croissant 70
Gnocchi 70
Millet, sorghum 70
Mush 70
Pealed boiled potatoes 70
Polenta, cornmeal 70
Puffed amaranth 70
Refined cereals (with sugar added) 70
Risotto 70
Special K™ 70
Tacos 70
Whole brown sugar 70
Baguette white bread 70
Brioche 70
Chocolate bar (with sugar added) 70
Corn flour 70
Dried dates 70
Matzo bread (white flour) 70
Molasses 70
Noodles (tender wheat) 70
Plantain/cooking banana/platano (cooked) 70
Potato chips, crisps 70
Ravioli (soft wheat) 70
Rice bread 70
Rusk 70
Standard rice 70
White sugar (sucrose) 70
Chestnut flour 65
Couscous, semolina 65
Hovis, brown bread (with leaven) 65
Maple syrup 65
Mars®, Sneakers®, Nuts®, etc. 65
Pain au chocolat 65
Pineapple (tin/can) 65
Raisins (red and golden) 65
Sorbet (with sugar added) 65
Sweet corn, corn 65
Tropical yam -US-, yam 65
Unpeeled boiled/steamed potato 65
Beet, beetroot (cooked) 65
Chinese noodles/vermicelli (rice) 65
Fava bean, broad bean, horse bean (cooked) 65
Jam (with sugar added) 65
Marmalade (with sugar) 65
Muesli (with sugar or honey added…) 65
Panapen, breadfruit, breadnut 65
Quince (preserve/jelly, with sugar) 65
Rye bread (30% of rye) 65
Spelt, einkorn 65
Tamarind, Indian date (sweet) 65
Unpeeled boiled/steamed potato 65
Whole-grain bread 65
Apricots ( tin/can with syrup) 60
Chestnut 60
Honey 60
Lasagna (hard wheat) 60
Mayonnaise (industrial, sweetened) 60
Milk loaf, milk white 60
Ovomaltine 60
Perfumed rice (jasmine…) 60
Powder chocolate (with sugar) 60
Bananas (ripe) 60
Hard/durum wheat semolina 60
Ice cream (regular, with sugar added) 60
Long-grain rice 60
Melons (cantaloupe, honeydew, etc.) 60
Oatmeal, porridge 60
Pearl barley 60
Pizza 60
Ravioli (hard wheat) 60
Bulgur wheat (cooked) 55
Grape juice (unsweetened) 55
Ketchup 55
Manioc, mandioca, yucca, Cassava (bitter) 55
Mustard (sugar added) 55
Papaya (fresh fruit) 55
Red rice 55
Sushi 55
Butter cookies, shortbread, spritz biscuit (flour, butter, sugar) 55
Japanese plum, loquat 55
Mango juice (unsweetened) 55
Manioc, mandioca, yucca, cassava (sweet) 55
Nutella® 55
Peaches (tin/can, with syrup) 55
Spaghetti (well cooked) 55
Tagliatelle (well cooked) 55
All Bran™ 50
Basmati rice 50
Bread with quinoa (approximately 65% of quinoa) 50
Cereal bar, energetic (no sugar added) 50
Cranberry juice (unsweetened) 50
Kiwifruit, monkey peach 50
Macaronis (durum wheat) 50
Muesli (no sweet) 50
Pineapple juice (unsweetened) 50
Wasa™ light rye 50
Whole wheat pasta 50
Apple juice (unsweetened) 50
Biscuit (whole flour, no sugar added) 50
Brown rice, unpolished rice 50
Chayote, chocho, pear squash, christophine 50
Jerusalem artichoke 50
Litchi (fresh fruit) 50
Mango (fresh fruit) 50
Persimmon, kaki-persimmon 50
Sweet potatoes 50
Whole couscous/semolina 50

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[learn_more caption=”Intermediate Glycemic Index Foods (GI 35-50)”]

Brown basmati rice 45
Coconut 45
Farro flour (integral) 45
Grapes, green and red (fresh fruit) 45
Jam (no sugar added, grapefruit juice sweetened) 45
Kamut flour (integral) 45
Orange juice (fresh squeezed and unsweetened) 45
Plantain/cooking banana/platano (raw) 45
Rye (integral; flour, bread) 45
Spelt, einkorn (integral) 45
Toasted integral bread 45
Whole bulgur wheat (cooked) 45
Whole couscous, whole semolina 45
Bananas (unripe) 45
Capellini pasta 45
Cranberry 45
Grapefruit juice (unsweetened) 45
Green peas (tin/can) 45
Kamut bread 45
Muesli Montignac 45
Pineapple (fresh fruit) 45
Plantain/cooking banana/platano (raw) 45
Sandard Pumpernickel bread 45
Spelt, einkorn (integral) 45
Tomato sauce (with sugar) 45
Whole cereals (no sugar added) 45
Bread, 100% integral flour with pure leaven 40
Buckwheat, kasha, saracen (integral; flour or bread) 40
Coconut milk 40
Dried plums/prunes 40
Falafel (fava beans) 40
Fava beans, broad beans, horse beans (raw) 40
Kidney/pinto beans (tin/can) 40
Matzo bread (integral flour) 40
Oat flakes (uncooked) 40
Peanut butter (no suger addes) 40
Quince (preserve/jelly, without sugar) 40
Shortbread, spritz biscuit (integral flour, no sugar added) 40
Tahin 40
Al dente spaghetti (5 min cook) 40
Brut cider 40
Carrot juice (unsweetened) 40
Dried fig 40
Egyptian wheat, kamut 40
Farro 40
Integral wheat pasta, al dente 40
Lactose 40
Montignac Pumpernickel 40
Oats 40
Pepino dulce, melon pear 40
Quinoa flour 40
Sorbet (unsweetened) 40
Adzuki/azuki bean 35
Amaranth, seeds 35
Apple stew, apple sauce 35
Cassoulet (meat and beans French dish) 35
Chick pea flour 35
Chinese noodles/vermicelli (hard wheat), noodles 35
Custard apple, cherimoya, sherbet fruit, soursop, guanabana 35
Dried apples 35
Dried tomatos 35
Falafel (chick peas) 35
Green peas (fresh) 35
Ice cream (with real fructose) 35
Kidney/pinto beans 35
Nectarines (fresh fruit) 35
Peaches (fresh fruit) 35
Pomegranate (fresh fruit) 35
Quinoa, hie 35
Sunflower seeds 35
Tomato sauce (natural, no sugar added) 35
White almond paste/puree (unsweetened) 35
Wild rice 35
Yoghurt 35
Ale strains 35
Apple (fresh fruit) 35
Black beans 35
Celeriac, knob celery, turnip rooted celery (raw) 35
Chick peas, garbanzo beans (tin/can) 35
Cranberry bean, borlotti bean, Roman bean 35
Dijon type mustard 35
Dried apricots 35
Essene/ezekiel bread (sprouted cereals bread) 35
Figs; Indian/barbary fig (fresh fruit) 35
Green peas (fresh) 35
Indian corn 35
Linum, sesame (seeds) 35
Oranges (fresh fruit) 35
Plums, prunes (fresh fruit) 35
Quince (fresh fruit) 35
Soy yogurt (fruit flavored) 35
Tomato juice 35
Wasa™ fiber (24%) 35
White beans, haricot beans, cannellini beans, faziola beans 35
Yeast 35

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[learn_more caption=”Low Glycemic Index Foods (GI <35)”]

Bread (Montignac integral bread) 34
Almond milk 30
Beet (raw) 30
Carrots (raw) 30
Chinese noodles/vermicelli (made from soy or mung beans) 30
Garlic 30
Marmalade (no sugar added) 30
Oat milk (non cooked) 30
Pears (fresh fruit) 30
Curd cheese 30
Soy milk 30
Tomatoes 30
Yellow lentils 30
Apricots (fresh fruit) 30
Brown lentils 30
Chick peas, garbanzo beans 30
French beans, string beans 30
Grapefruit, pummelo, shaddock (fresh fruit) 30
Milk 30
Passion fruit, maracuja, granadilla 30
Powdered/fresh milk 30
Scorzoneras 30
Tangerines, madarines, satsuma 30
Turnip (raw) 30
Blanched barley 25
Cherries 25
Flageolet beans, fayot beans 25
Green lentils 25
Mung beans, moong dal 25
Raspberry (fresh fruit) 25
Seeds (squash/marrow) 25
Split peas 25
Whole-almond paste/puree (unsweetened) 25
Blackberry, mulberry 25
Blueberry, whortleberry, bilberry 25
Dark chocolate (more than 70% of cocoa content) 25
Gooseberry 25
Hummus, homus, humus 25
Peanut paste/puree (unsweetened) 25
Redcurrant 25
Soy flour 25
Strawberries (fresh fruit) 25
Whole-hazelnut paste/puree (unsweetened) 25
Artichoke 20
Chocolate, plain (>85% of cocoa) 20
Heart of palm, cabbage palm 20
Lemon juice (unsweetened) 20
Montignac sugarless jam 20
Ratatouille 20
Soy “cream” 20
West Indian cherry, acerola 20
Bamboo shoot 20
Eggplant, aubergine 20
Lemon 20
Montignac Real fructose, fruit sugar 20
Powder cocoa (no sugar added) 20
Soy yogurt (unflavored) 20
Tamari sauce (unsweetened) 20
Almonds 15
Black currant 15
Broccoli 15
Cabbage 15
Cashew nut, acajou 15
Celery 15
Chicory, endive 15
Courgettes, zucchini 15
Fennel 15
Hazelnuts, filberts, Barcelona nuts 15
Mushroom, fungus 15
Onions 15
Pesto 15
Pickle 15
Pistachio, green almond 15
Rhubarb 15
Salad, lettuce 15
Shallot, echalot, Spanish garlic 15
Soya 15
Spinaches 15
Sweet peppers (red, green), paprika 15
Tofu, soybean curd 15
Wheat germ 15
Agave (syrup) 15
Asparagus 15
Bran (oat, wheat…) 15
Brussels sprouts 15
Carob powder 15
Cauliflower 15
Cereal shoots (soy or mung bean sprouts, etc.) 15
Chili pepper 15
Cucumber 15
Ginger 15
Leeks, scallions 15
Olives 15
Peanuts 15
Physalis, golden gooseberry, Cape gooseberry, Chinese lantern, husk tomato 15
Pine seed 15
Radish 15
Runner beans, Italian flat beans 15
Sauerkraut, sourcrout 15
Sorrel dock 15
Spinach beet, perpetual spinach 15
Sprouted seeds 15
Tempeh 15
Walnuts 15
Low GI Montignac pasta (spaghetti) 10
Avocado 10
Low GI Montignac spaghetti 10
Crustaceans 5
Vinegar 5
Spices (parsley, basil, oregano, cinnamon, vanilla, etc.) 5

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In general, refined grain products and potato have a high GI, exceeding that of table sugar by up to 50%, whereas most vegetables, fruits and legumes have a low GI.  Other factors including carbohydrate type, fiber, protein, fat, food form and method of preparation, determine the GI of a particular food.

According to data from the Department of Agriculture, >80% of the carbohydrate currently consumed by children ages 2–18 has a GI equal to or greater than that of table sugar.  Moreover, carbohydrate absorption rate (and therefore GI) is increased after a low fat meal because fat acts to delay gastric emptying.

The rapid absorption of glucose from the high GI meal results in a high insulin secretion; which promotes uptake of glucose in muscle, liver and fat tissue and inhibits fat breakdown (lipolysis).  In the post absorptive period, a transient hypoglycemia ensues, with blood sugars falling below normal due to high insulin, resulting in hunger and agitation.  In some individuals, this may cause tremendous anxiety, which may create a feedback loop of carbohydrate addiction. Experimental evidence also suggests that elevated insulin levels, even just for 48–72-h period (in the presence of normal or reduced blood sugar levels) decreases insulin sensitivity in healthy subjects creating a diabetic effect of insulin resistance.

Without a doubt, high GI foods elicit (calorie for calorie) higher insulin levels than low GI foods.  In humans, high acute insulin secretion after intravenous glucose tolerance tests predicts weight gain.  High insulin levels also reduce Growth Hormone levels, which may reduce metabolic rate. Hormonal responses to a high GI diet stimulate hunger and favor storage of fat, which promotes excessive weight gain.

 

The LiveHealthProtocol dietary recommendation is designed to lower the insulin response to ingested carbohydrate (low GI), which improves access to stored metabolic fuels, decreases hunger, and promotes weight loss. The LiveHealthProtocol recommends abundant quantities of vegetables, and fruits, moderate amounts of protein and healthful fats, and decreased intake of refined grain products, potato and concentrated sugars.

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  • Milk products (whey protein) have a GI which is low, but have paradoxic high insulinemic index (release high amounts of insulin).  Milk products appear insulinotropic as judged from 3-fold to 6-fold higher insulinemic indexes than expected from the corresponding glycemic indexes.  So even if you are consuming a low GI milk product, from the insulin standpoint it is a very high load.


  • Starchy fruits increase their Glycemic Index depending on ripeness.  Green bananas have low GI of 40 but when they are ripen it will raise to 65.


  • Glycemic Load [GL] relates the GI to the amount of carbohydrate eaten in a normal serving or in 100 grams.  It measures the total amount of carbohydrate, and is decreased by fiber consumption.

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Not all calories are the same.

Carbs are an addiction.

Serotonin release in the brain controls functions such as sleep onset, pain sensitivity, blood pressure regulation, and control of mood.  Serotonin-releasing neurons are unique in that the amount of neurotransmitter they release is normally controlled by food intake: Carbohydrate consumption–acting via insulin secretion and the “plasma tryptophan ratio”–increases serotonin release dramatically (by enhancing the brain uptake of its precursor, tryptophan).  Elevated serotonin causes significant mood enhancement and a generalized sense of contentedness.  Patients learn to overeat carbohydrates (particularly snack foods and drinks, like soda, potato chips or pastries, which are rich in carbohydrates) to make themselves feel better.

Self-medication with carbohydrate rich foods as though they were drugs is a frequent cause of weight gain, and is often seen:

  • In patients who become fat when exposed to stress
  • In women with premenstrual syndrome (PMS)
  • In patients with “winter depression” (Seasonal Affective Disorder)
  • In patient’s who are experiencing chronic pain (ingestion analgesia)
  • In people who are attempting to give up smoking. (Nicotine increases brain serotonin secretion; nicotine withdrawal has the opposite effect causing cravings.)
  • As a consequence of chronic patterned carbohydrate consumption causing hardwired changes in neurons, such that there are cravings and feelings of withdrawal when carbohydrates are withheld

Carbohydrate load is so closely linked to addiction, that the Glycemic Index (GI) of specific carbohydrates correlates closely with their relative addictive strength  and activates addiction neural pathways.

The take home message, carbohydrates are an addiction.  Carbohydrate consumption promotes neurochemical changes, which reinforce additional carbohydrate consumption.  There is now evidence that carbohydrate binging is akin to heroin addiction, with the cravings for carbohydrates reduced by opiates and more interestingly, carbohydrate cravings dramatically increased during opiate withdrawal.  Unfortunately, carbohydrate addiction will definitely make you fat.

The addictive power of carbohydrates.

Your brain and obesity.

Obese people have, on average, eight percent less brain tissue than people of normal weight, according to a new study published in the journal Human Brain Mapping.  Even overweight people have four percent less brain tissue than their normal-weight peers.   Obesity is independently associated with poor educational attainment and may be responsible for the cognitive deficiency manifested in lower intelligence test scores (IQ).  Excessive body weight gain has a shrinking and aging effect on the brain with a reduction in measureable IQ, in addition to the previously recognized increased risk of diabetes, high blood pressure, heart disease and stroke.  The terminology of obesity and ever weight is defined by using weight and height to calculate a number called the Body Mass Index (BMI).  Obesity is defined as a BMI greater than 30, and overweight is defined as a BMI of 25 to 29.9.

 

 

The new study showed that age, gender, and race don’t matter. MRI brain scans of obese people revealed that their brains are smaller (atrophy) and appeared to be 16 years older than brains of lean people. The brains of overweight people appeared to be 8 years older. The presence of brain shrinkage is associated with dementia and depletes cognitive reserves in later years, which puts you at greater risk of Alzheimer’s and other diseases that attack the brain.

Atrophy or shrinkage of brain tissue associated with obesity and Alzheimer's

 

The primary areas of the brain affected include the frontal and temporal lobes, which are responsible for planning and memory.

 

The mechanisms which links obesity to gray matter atrophy (brain shrinkage) include:

  • Reduced blood flow to brain due to blood vessel shrinkage
  • Reduced perfusion due to hypertension and loss of vessel elasticity
  • Toxic xenoestrogens released from excessive adipose tissue
  • Insulin resistance with chronically elevated blood glucose, leading to glycation, inflammation, and protein degradation
  • Expansion of the penumbra zones (enlargement of the stroke zone), possibly even with micro strokes or silent strokes.

 

 

This lack of blood flow to the brain causes cell and tissue death resulting in brain shrinkage. Interestingly, the research also showed that regular, vigorous exercise has the reverse effect. Physical activity can actually conserve brain tissue, which further supports the idea that blood flow is at least partly responsible for the maintenance or shrinkage of our brains. Of course, exercise also helps greatly in preventing obesity and its related conditions and risks.

 

According to the World Health Organization, a poor dietary habit with reliance on convenience and processed foods significantly contributes to obesity.  The lack of portion size control is a particular problem in the United States, where “Super Sizing” every restaurant meal has contributed to our expanding waistlines.  Additionally, food engineering and tremendous food diversity titillates our taste buds into over consumption.

 

These new study results highlight the importance of exercising regularly, eating a balanced diet of fresh, whole foods and limiting your portion sizes. Not only will these healthy habits go a long way towards maintaining your weight and reducing the risks associated with obesity, they can help you maintain a healthy brain – which will end up affecting much more than how you look.

Brain shrinkage and reduced IQ is associated with obesity. It may be reversible with appropriate diet and nutrition.

The effects of smoking on your brain.

If you thought the only dangers of smoking were chronic obstructive pulmonary disease (COPD), emphysema and lung cancer, think again. New studies now link the expensive (financially and health-wise) habit with new concerns.

One recent paper, “Smoking History and Cognitive Function in Middle Age From the Whitehall II Study,” appeared in the Archives of Internal Medicine. Head investigator, Séverine Sabia, MSc—from the Institut National de la Santé and de la Recherche Médicale in Villejuif, France— looked at recent discussions linking smoking with dementia, considered related through the effect smoking has on vascular disease.

 

The Whitehall II study evaluated over 10,000 participants, aged 35-55 (at baseline, phase 1, 1985-1988). Assessments were made on smoking history at both phase 1 and phase 5 (1997-1999). Among the group, 25% were light smokers (≤ 5 cigarettes per day) and 25% were heavy smokers (1-2 packs per day). Smokers had an average of 14 cigarettes daily; only 27 participants smoked over two packs a day.

Cognitive data (memory, reasoning, vocabulary and semantic/phonemic fluency) were available for 5,388 study subjects at phase 5—when participants were 45-68 years old/mean age 55.5. Of those, 4,659 were retested 5 years later for phase 7, when study subjects were 50-74 years old/mean age 61

• Smoking was associated with greater risk of poor memory.
• After adjustments at phase 5, smokers had a 37% higher risk for cognitive decline.
• Long-term ex-smokers (stopped prior to study) demonstrated a 30% lower risk for poor cognition (vocabulary decline and reduced verbal fluency)—possibly due to health behavior improvements.
• Positive midlife health changes (better nutrition, exercise, alcohol consumption, etc.) and smoking cessation were linked.
• Middle-aged smokers are more likely to be lost to follow-up by death or through nonparticipation in cognitive tests. Therefore, the smoking-decline cognition link could be undervalued.
• Additional research indicates that mild cognitive decline continues at an accelerated rate to clinically diagnosed dementia.
• A 2007 meta-analysis of 19 studies of over 26,000 elderly (mean age 74) demonstrated that current smoking increased risk for dementia and cognitive decline by 40%-80%, depending upon measure employed.
• A ten-year study of over 3,600 Australians demonstrated a four-fold increased risk of age-related macular degeneration compared to non-smokers.
• A June 2008 study showed that smokers have higher all-cause mortality, equivalent to a non-smoker 5-10 years older.

 

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The excuse of weight gain:
One objection smokers often give for not quitting is weight gain. That may be true for light smokers (less than one pack per day), but heavy smokers (greater than one pack per day) tend to have other associated health habits, such as weighing more and having an increased risk for metabolic syndrome and diabetes. The bottom line: Smoking shows no benefits on any level.

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Smoking is counterproductive to healthy aging. You can stay active, alert, lean and healthy with established protocols, shown to improve cognitive function and physical/sexual energy as well as enhance libido and body composition (lean muscle mass, reduced body fat), strengthen your immune system and ability to manage stress.

Smoking makes you stupid.