While there is a clear genetic predisposition for some individuals to develop autoimmune disorders, there are also significant environmental interactions, with a near epidemic rise in autoimmune disorders and food allergies in the industrialized world occurring in less than fifty years. Access to clean water, safe food, sanitation, and modern medical care in the last century has led to a near elimination of parasitic infections in modern cultures. Unfortunately, improved sanitation has also been closely associated with an increase in hypersensitivity and autoimmune disorders such as Multiple Sclerosis, Crohn’s, and peanut allergies. It should be noted that tropical and subtropical parts of the world with poor sanitation have high numbers of people with ongoing parasitic infection and extremely low incidences of inflammatory diseases. Additionally when immigrants relocate to the western world with its pristine sanitation, the next generation develops autoimmune disorders and food allergies similar to the industrialized world.
The “hygiene hypothesis,” suggests that parasitic worms fine tune the human immune systems and protect against allergies and autoimmune diseases. Parasites have co-evolved to manipulate their environments so they can live and reproduce without causing the illness or death of their host. By mediating the immune system’s attack against them, parasites can live and reproduce comfortably. Parasites release substances that interact with the host’s chemistry, and the human immune system has slowly adapted to the presence of certain intestinal parasites. By removing the worms and the inhibitory effect that they have on inflammation, the human body can overproduce inflammatory agents, resulting in autoimmune disease.
Autoimmune reactions occur when the immune system launches an attack at something that is not harmful, either a substance in the environment or the individual’s own tissues. Exposure to certain organisms in our natural environment teaches the human immune system which things it needs to respond to and which things it can safely ignore. Exposure to helminthic parasites triggers the fine-tuning of the immune system and teaches it to tolerate the parasite, as well as some overlapping antigens seen in Multiple Sclerosis, Crohn’s and peanut allergies. If the immune system is never exposed to helminths and other fecal microorganisms, it doesn’t mature properly and resulting in an exaggerated response, and development of allergies and autoimmune diseases.
Other autoimmune mediated diseases that may be reduced by parasitic infections include Alzheimer’s disease, asthma, atherosclerosis, some cancers, eczema, hay fever, Parkinson’s disease, type one diabetes, celiac disease, rheumatoid arthritis, and ulcerative colitis.
The use of helminthic therapy with hookworm and TSO is being currently investigated. Data suggests that Multiple Sclerosis, Crohn’s and severe peanut allergies all benefit from induced parasitic infections.
Obesity is among the most important medical problems in the United States today. Currently, 1 in 4 children and 1 in 2 adults are overweight, and prevalence rates that have increased by 50% since the 1960s. The Federal government and various official medical agencies, at the behest of grain producers, have advocated decreasing intake of total fat, while increasing consumption of “complex carbohydrate.” Consumption of carbohydrates has increased over the years, and the nation’s levels of obesity, Type 2 diabetes and heart disease have dramatically risen. Americans, on average, eat 250 to 300 grams of carbs a day, accounting for about 55% of their caloric intake.
All carbohydrates (a category including sugars) convert to sugar in the blood, and the more refined the carbs are, the quicker the conversion. When you eat a glazed doughnut or a serving of mashed potatoes, it turns into blood sugar very quickly. To manage the blood sugar, the pancreas produces insulin, which pushes glucose from the blood stream into cell to be used for energy conversion or storage.
When cells become more resistant to those insulin instructions, the pancreas needs to make more insulin to push the same amount of glucose into cells. As people become insulin resistant, carbs become a bigger challenge for the body. When the pancreas gets exhausted and can’t produce enough insulin to keep up with the glucose in the blood, diabetes develops
The first sign of insulin resistance is a condition called metabolic syndrome — a red flag for impending diabetes and heart disease. Metabolic syndrome (found in nearly 1/4 of adults) is diagnosed when people have three or more of the following:
high blood triglycerides (more than 150 mg)
high blood pressure (over 135/85)
central obesity (a waist circumference in men of more than 40 inches and in women, more than 35 inches)
low HDL cholesterol (under 40 in men, under 50 in women)
elevated fasting glucose.
Glycemic Index measures the “effect of food on blood glucose levels.” It is a ranking of foods based on the how quickly the blood sugar levels will increase after ingestion. A low glycemic food gives a slow increase in blood sugar levels. A high glycemic index food gives a more rapid rise in blood sugar levels.
GI is specifically defined as the measurable glucose response curve after consumption of 50 g carbohydrate from a test food, divided by the response after consumption of 50 g glucose.
The GI for glucose would be defined as 100.
High GIs are above 50
Intermediate GIs range between 35 and 50
Low GIs are below or equal to 35
[learn_more caption=”High Glycemic Index Foods (GI>50)”]
In general, refined grain products and potato have a high GI, exceeding that of table sugar by up to 50%, whereas most vegetables, fruits and legumes have a low GI. Other factors including carbohydrate type, fiber, protein, fat, food form and method of preparation, determine the GI of a particular food.
According to data from the Department of Agriculture, >80% of the carbohydrate currently consumed by children ages 2–18 has a GI equal to or greater than that of table sugar. Moreover, carbohydrate absorption rate (and therefore GI) is increased after a low fat meal because fat acts to delay gastric emptying.
The rapid absorption of glucose from the high GI meal results in a high insulin secretion; which promotes uptake of glucose in muscle, liver and fat tissue and inhibits fat breakdown (lipolysis). In the post absorptive period, a transient hypoglycemia ensues, with blood sugars falling below normal due to high insulin, resulting in hunger and agitation. In some individuals, this may cause tremendous anxiety, which may create a feedback loop of carbohydrate addiction. Experimental evidence also suggests that elevated insulin levels, even just for 48–72-h period (in the presence of normal or reduced blood sugar levels) decreases insulin sensitivity in healthy subjects creating a diabetic effect of insulin resistance.
Without a doubt, high GI foods elicit (calorie for calorie) higher insulin levels than low GI foods. In humans, high acute insulin secretion after intravenous glucose tolerance tests predicts weight gain. High insulin levels also reduce Growth Hormone levels, which may reduce metabolic rate. Hormonal responses to a high GI diet stimulate hunger and favor storage of fat, which promotes excessive weight gain.
The LiveHealthProtocol dietary recommendation is designed to lower the insulin response to ingested carbohydrate (low GI), which improves access to stored metabolic fuels, decreases hunger, and promotes weight loss. The LiveHealthProtocol recommends abundant quantities of vegetables, and fruits, moderate amounts of protein and healthful fats, and decreased intake of refined grain products, potato and concentrated sugars.
Milk products (whey protein) have a GI which is low, but have paradoxic high insulinemic index (release high amounts of insulin). Milk products appear insulinotropic as judged from 3-fold to 6-fold higher insulinemic indexes than expected from the corresponding glycemic indexes. So even if you are consuming a low GI milk product, from the insulin standpoint it is a very high load.
Starchy fruits increase their Glycemic Index depending on ripeness. Green bananas have low GI of 40 but when they are ripen it will raise to 65.
Glycemic Load [GL] relates the GI to the amount of carbohydrate eaten in a normal serving or in 100 grams. It measures the total amount of carbohydrate, and is decreased by fiber consumption.
Optimizing fat burning while simultaneously building muscle should be the goal of any effective exercise program, the critical linkage between exercise and the food we eat is ATP. This article describes the importance of understanding what ATP is, and how different foods are converted to ATP, and when different fuels (protein, carbohydrate, or fat) are used for energy. Understanding these concepts provides the blueprint for the LiveHealthProtocol.com diet and exercise guidelines.
I frequently talk to patients about the foods they eat, and how it impacts their health. I think its very important to understand that converting food to usable energy is far more than simply chewing big pieces of food, which are digested into small pieces, and used directly by the cells. Your body does not directly take the food particles it consumes and transfers them to your cells for metabolism. It converts these particles to fundamental substrates, which are then converted to ATP (adenosine triphosphate), which is the actual fuel for your cells.
(Other substrates are used for structural growth and for cofactors, as well as immune recognition purposes; but the apple you eat does not become a little apple that your cells consume, it instead converts to sugars, proteins, and fats which are metabolized to ATP, which power your cells.)
The universal currency for life is ATP, the energy-carrying molecule found in the cells of all living things. ATP functions like a tiny battery debit card, an ATP molecule consists of adenosine and three negatively charged inorganic phosphate groups when it is fully charged and ADP (adenosine diphosphate) when it has released its energy and has only two phosphates.
Recharging ADP to ATP requires fuel substrates, which is the converted food that you eat, whether it be protein, carbohydrate, or fat. The exact recharging is coupled to the molecular destruction of Carbon bonds, similar to gasoline combustion in your car.
The recharging of ADP to ATP is what couples the food you consume to usable energy, the discharging of ATP to ADP transfers energy to usable cellular function for either chemical or mechanical reactions. Available ATP (and Phospho Creatine- a related Phosphate storage bank in muscle) is depleted within 15 seconds of vigorous exercise.
Substrate to ATP
There are three significant fuel sources or substrates of energy to reform ATP from ADP.
Carbohydrates are metabolized to glucose, which quickly regenerates ADP to ATP through a process called glycolysis. Consumed carbohydrates are directly available as glucose, or excessive consumed carbohydrates are stored in muscle and liver as glycogen for later reconversion to glucose. (Excessive carbohydrates in the presence of insulin are also converted to fat in fat cells.) Use of carbohydrates for energy does not require large amounts of oxygen and can occur even during anaerobic conditioning. Production of lactate and lactic acid occur with use of carbohydrates for fuel. Available carbohydrates provide energy to recharge ATP for the first 45-60 seconds of high intensity therapeutic exercise.
Fat is a slow energy release form, typically stored in fat cells. Lipolysis is the term used to describe the breakdown of fat (triglycerides) into the more basic units of glycerol and free fatty acids, which then undergo beta-oxidation. Combustion of fatty acid molecules produces significantly more ATP, compared to glucose molecules. However, because fatty acids consist of more carbon atoms than glucose, they require more oxygen for their combustion. Fatty acids are oxidized by most of the tissues in the body; except, the brain, red blood cells, and the adrenal medulla. It is a huge storage reservoir, but is too slowly released for immediate energy utilization. Lipolysis provides energy after the first 60 seconds of exercise, but only effectively in the presence of large amounts of oxygen.
Protein can also be used as an energy source, but it must first be broken down to amino acids before being converted to glucose. Protein is thought to make only a small contribution (< 5%) to energy production, but up to 18% of total energy requirements during long strenuous activity, sometimes characterized as rhabdomyolysis.
The Physicians’ Health Study from Brigham and Women’s Hospital (Boston, MA) reveals that as little as seven extra pounds combined with little or no exercise can significantly increase your risk of heart failure and sudden cardiac arrest.
Regardless of the level of activity, higher body mass index equates to higher heart failure risk.
Even modestly overweight men had increased heart risk—a risk that increased with excess pounds.
Every 7 pounds of excess weight equated to a 11% increased heart risk in the 20 year study—1 kg/m2 increase in BMI, men over 5’10” tall in a multivariate analysis.
Overweight study participants had a 49% heart failure increase.
Obese study participants had a 180% heart failure increase.
18% reduction in heart failure risk in active men—with one to three times per month of physical activity.
36% reduction in heart failure in higher activity men—those with five to seven times per week of physical activity.
A higher BMI increased heart failure risk in both active and inactive men, the “beneficial effect of vigorous physical activity in reducing the risk of heart failure was observed in lean, overweight and also obese men.” The American Heart Association says: Healthy adults ages 18-65 should get at least 30 minutes of moderate intensity activity five days per week.
Couch potatoes—physically inactive people—are more likely to develop heart disease or have a stroke.
Two-thirds of Americans have excess body weight—and about only 30% exercise regularly.
660,000 new cases of heart failure are diagnosed each year in the U.S.
80% of men and 75% of women aged 65 and older diagnosed with heart failure die within eight years.
Too much belly fat ups risk for other health problems: high blood pressure, high blood cholesterol, high triglycerides, diabetes, heart disease and stroke.
Women with excess body fat are at higher risk of heart disease — even if they don’t have other risk factors.
Even just walking 30 minutes a day can . . .
Reduce coronary heart disease risk
Reduce the risk on non-insulin dependant [Type 2] diabetes
Improve blood pressure and blood sugar levels
Improve blood lipid profile
Maintain body weight and reduce your risk of obesity
Enhance mental well-being
Reduce the risk of osteoporosis
Reduce the risk of breast and colon cancer
Even a minimum duration of 10 min, high intensity exercise at an anaerobic or lactate threshold production level increases circulating Growth Hormone in adults. Increasing Growth Hormone results in enhanced production of Thyroid Hormone and Testosterone, with improved vessel elasticity. The risk of death was reduced by 50% with an improved exercise capacity attained of just 30 minutes per session, 5-6 days per week. And even if 30 minutes was too much , splitting the routine into 10-15 minute segments (morning/evening) gives the same benefit.
Even reducing your weight just a few pounds or exercising even ten minutes a day can have a huge impact. For more information regarding high intensity exercise check out the article on “Exercise as if your life depended upon it!”
For information on how to lose weight, guaranteed, got to mdHCG.com.
As your Body Mass Index [BMI] increases, so does your risk of death. But is BMI the best tool to determine your health status?
Calculated from your weight and height, BMI provides a general gauge of body fatness. BMI is a correlation between an individual’s height and weight, but it does not distinguish between fat weight and muscle weight.
Figure your Body Mass Index using either your bioempedence scale, your body fat calipers or the following simple formula:
BMI=Weight in pounds x 703, divided by height in inches x height in inches
BMI=[Weight x 703]/height2
Weight in pounds = 150
Height in inches = 64
150 x 703 = 105,450
64 x 64 = 4096
105,450/4096 = 25.74
BMI = 25.74%
Your BMI number can fall into one of four adult categories:
Below 18.5 = Underweight
18.5 – 24.9+ = Normal
25.0 – 29.9 = Overweight
30.0 and above = Obese
As your BMI increases, so does your risk of death from many possible causes, such as ischemic heart disease, stroke and various types of cancers. Based upon a study published in the online March 2009 Lancet, a collaborative analysis of 57 studies found that BMI is a “reasonably good measure” of general adiposity – body fat.
Researchers reported the lowest mortality was in those with a BMI of 22.5 to 25 kg/m2. As BMI slightly increases, the mortality rate begins to skyrocket. each 5 kg/m2 higher BMI was associated with about 30% higher all-cause mortality (40% for vascular; 60–120% for diabetic, renal, and hepatic; 10% for neoplastic; and 20% for respiratory and for all other mortality). In other words, as BMI increased overall death rate increased.
Having an above normal range BMI can result in these health conditions:
Coronary heart disease
People frequently state that muscle weighs more than fat. Its simply not true, a pound of muscle weighs exactly the same as a pound of fat. It just so happens that fat occupies nearly 18% more volume for the same pound weight, and muscle tends to adhere to tightly to skeletal structures, whereas fat drapes loosly. Because BMI fails to distinguish between fat and muscle, because it is weight based, a better way of looking at this was needed, hence a calculation of actual percentage fat by bioimpedance scale or skin calipers or more scientifically with DEXA scan.
Danger also lurks behind that expanding waistline: highly active, toxic abdominal fat heightens your disease risk. Check your waist girth with a tape measure, starting at the top of the hipbone. Measure at your greatest waist area, keeping the tape measure even, not pulling too tightly. A total of over 40 inches for men or over 35 inches for women means it’s high time to get serious about taking control of your health and future. The abdominal girth or waist measurement is a quick tool in determining your cardiac risk, it looks more at the volume of fat in the abdomen rather than the weight.
The waist to hip ratio is an important tool that helps you determine your overall health risk. People with more weight around their waist are at greater risk of lifestyle related diseases such as heart disease and diabetes than those with weight around their hips. It is a simple and useful measure of fat distribution.
Use a measuring tape to check the waist and hip measurements. - Measure your hip circumference at it’s widest part. - Measure your Waist Circumference at the belly button or just above it.
Simply take your waist measurement / your hip measurement; for example:
Waist to hip ratio:
Waist circumference / hip circumference
Ratio: 32/30 = 1.07
MALE FEMALE: Health risk based on ratio only
.95 or below .80 or below Low Risk
.96 – 1.0 .81-.85 Moderate Risk
1.0 + .85 + High Risk
Perhaps exercise tolerance and maximal exercise capacity by measuring METs may be the best indicator of body health and longevity, a functional test of exercise capacity rather than a weight test or a size test.
If you are truly interested in losing abdominal fat, check out our mdHCG protocol for a guaranteed solution.
Exercise as if your life depends upon it, it really does. Men who achieved >7 METs (highly to very highly fit) level demonstrated a 50%-70% lower mortality risk than “low fit” subjects.
In a study published in the Journal Circulation, researchers assessed “the association between exercise capacity and mortality” in over 14,000 men—subjects whose average age was 60, who did or didn’t have cardiovascular disease and who successfully completed a treadmill test. Men who achieved >7 METs (highly to very highly fit) level demonstrated a 50%-70% lower mortality risk than “low fit” subjects.
The highest-intensity aspect of exercise, the hardest part. is the 15 seconds of sprinting at the end of a long run, or the most difficult 10 seconds of pumping during a peak level on an exercise bike, or the last few repetitions when exercising muscles to failure. One “metabolic equivalent” [MET] is the amount of oxygen used by an average person at rest and increases proportionally with the intensity of exercise.
A MET is used as a practical means of expressing the intensity and energy expenditure of physical activities in a way comparable among persons of different weight; but actual energy expenditure (e.g., in calories or joules) during a physical activity depends on the person’s body mass, therefore the energy cost of the same physical activity will be different for persons of different weight. In other words, METs as defined by most exercise equipment cannot be used to determine metabolic rate directly. Never the less, a physical activity with a MET value of 2, such as walking at a slow pace (e.g., 3 km/h) would require for a specific person twice the energy that person consumes at rest (e.g., sitting quietly), a MET value of 1.
In this study, fitness categories based on METs achieved are were:
low [5 METs]
moderate [5-7 METs]
highly [7.1 to 10METs]
very highly fit [over 10 METs]
Subjects exercised until tired; with follow-ups done for 7.5 years on average. Men who achieved >7 METs (highly to very highly fit)—demonstrated a 50%-70% lower mortality risk than “low fit” subjects. The chances of staying alive increased by 12 to 13 percent with each increase of a single metabolic equivalent [MET] when exercising as hard as possible on a treadmill. Peak MET achieved is a better predictor of how long someone will live than other factors – including health risk factors like high cholesterol, diabetes, smoking, high blood pressure, and even heart disease.
The risk of death was reduced by 50% with an improved exercise capacity attained of just 30 minutes per session, 5-6 days per week. And even if 30 minutes was too much , splitting the routine into 10-15 minute segments (morning/evening) gives the same benefit. Additionally, even moderate intensity exercise, greater then 7 METs offers significant health benefits.
Increased health span: A study following Harvard grads for 30 years showed those moderately active were at substantially decreased risk of death.
Decreased health risks: Strengthening the heart muscle for good circulation, decreased blood pressure and reduced stroke risk.
Reduced stress and significantly improved mood: With a moderate intensity workout of 20 minutes or more.
Increased muscle endurance: Making daily activities easier.
Improved sleep quality: Researchers at Stanford, Emory and the University of Oklahoma reported older people doing brisk walking and/or low-impact aerobics four times a week went to sleep faster and slept an hour longer than before (Harvard Health Letter, March 1997).
Many of these benefits accrue due to the improved endocrine profile; with resultant elevated Thyroid Hormone, Testosterone, and Growth Hormone. Insulin sensitivity also seems to be enhanced with improved glucose control, resulting in less fat deposition, increased fat mobilization as usable energy, and reduced total Insulin levels and elevated Glucagon levels.
The key element in obtaining health benefits is the high intensity nature of the exercise, and the relatively short duration of the exercise. MET capacity is even more important than the traditionally measured BMI or waist hip ratio.
If you are truly interested in losing abdominal fat, check out our mdHCG protocol for a guaranteed solution.
There are three types of fat commonly seen observed in the abdomen
Subcutaneous Fat, which is fat immediately below the skin but outside the abdominal cavity.
Retroperitoneal or Structural Fat separating organ and providing cushioning during movement.
Visceral abdominal fat (found inside the abdominal cavity). Most of that fat is found on the greater omentum—a large apron-like sheet that drapes over all the organs. Some people are prone to storing their body fat in their abdomen as part of this greater omentum. As a result, large, globule clumps of fat attach to the omentum, where they release toxic materials into the venous drainage and onto the bloodstream, ultimately causing adverse effects. This kind of fat releases adipokines, harmful chemicals that can cause Alzheimer’s, type 2 diabetes, insulin resistance, high blood pressure, and increased risk of cancer.
Reports have demonstrated that being overweight or obese (particular with a centralized distribution of adiposity) puts you in a higher-risk category for chronic conditions, from insulin resistance, type 2 diabetes, high blood pressure, high cholesterol, stroke, heart attack, congestive heart failure, gallstones, gout, osteoarthritis, sleep apnea and a liver disease called nonalcoholic fatty liver disease (NAFLD).
It is interesting to note that the middle-age bulge increase your chances of having
Alzheimer’s or other types of dementia in your senior years by nearly three times, even though it’s not your brain that stores the fat. This may be related to:
Toxic metabolites produced by the visceral abdominal fat, such as xenoestrogens which suppress testosterone formation, leading to poor blood vessel elasticity and high blood pressure
Storage of fat soluble toxins, such as food borne pesticides and herbicides, acquired from the environment which then slowly leach out.
Toxic belly fat is thought to promote amyloid accumulation by increasing chronic inflammation. Amyloid is an abnormal protein, which deposits in the body’s tissues or in more organ-specific areas, such as in the pancreas (type 2 diabetes) or central nervous system (Alzheimer’s, Parkinson’s, Huntington disease).
Visceral abdominal fat (belly fat) is the last reservoir people get rid of when they’re losing body fat—and it’s the first place they store it when they gain back body fat.
To date, there are no ways to specifically target that fat, but there are things you can do to work your way down to healthier body fat levels (16% for men, under 22% for women).
A low-glycemic nutrition eating plan with specific nutritional supplementation can help you optimize your health potential and reduce belly fat. Consistent high intensity interval exercise can increase metabolic rates, lower heart disease risk and improve body composition, muscle endurance, flexibility, cardiovascular endurance, core strength/stability and posture. These effects are not purely related to the energy burned due to exercise, but also due to the significant endocrine [hormonal changes] induced by resistance exercise leading to increased Growth Hormone, Thyroid Hormone, and Testosterone production.
More specifically, resistance training helps you lose abdominal fat and overall body fat while lowering cholesterol: Weight training is the best way to burn fat; it’s more effective for losing weight than aerobic activity because it burns calories while you’re exercising and later at rest due to the hormonal changes and muscular regeneration.
If you are truly interested in losing abdominal fat, check out our mdHCG protocol for a guaranteed solution.